Friday, March 29, 2019
Leukemia: Types and Treatment Options
Leukemia Types and Treatment Options background knowledge information Leukemia is a illness that has been affecting society these days. Ab bulge 119,280 newly cases ar being found out this year. Leukemia is a filiation crabmeat having to do with leukocytes, or as better known blank railway line cells, that take over the overdress marrow and spread throughout the declination stream in our personate. White job cells exist in our body to protect it against diseases and infections.thither ar five causes of white blood cells that go through the blood to the site of infection. These cells argon grouped into cardinal groups Granulocytes and Agranulocytes. Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.Neutrophils are granulocyte and are the most common White Blood cubicle (WBC) in the body. Its the first one to show up to ingest bacterium, virus particles, fungi, and protozoa. Eosinophils have a bilobed nuclei and uniform-sized cytosplamic granule. They moderate allergic reactions and defend against bloodsucking worm infestations. Basophilis is also a Granulocyte and the smallest of the three. They discharge their granules containing histamine and heparin into dam advanced waver spaces to promote inflammation and blood flow to damaged areas.Agranulocytes lacks granules in their cytoplasm. The two types of granulocytes are as follow Monocytes which travel through the blood for a day before even existing. The migrating monocytes are big eaters and they develop into macrophages and phagocytose bacteria debris in the tissue. Lymphocytes are grouped into T cells and B cells. T cells may directly attack foreign and tumor cells. B cells learn antibodies attack foreign cells or proteins. These are the cells that are affected when a person is diagnosed with leukemia.According to healthcommunities.com Leukemia is classified by how quickly it progresses. Acute leukemia is strong-growing and scu m bag overrun the body within a some weeks or months. By contrast, chronic leukemia is slow-growing and progressively worsens over years. The blood-forming cells of knifelike leukemia remain in an immature state, so they reproduce and accumulate very rapidly. on that pointfore, acute leukemia inescapably to be treated immediately otherwise the disease may be gameyal within a few months. Fortunately, some subtypes of acute leukemia react very well to available therapies and they are curable. Children often develop acute forms of leukemia, which are served differently from leukemia in full-growns.Chronic Leukemia is distinguished by the unwarranted build up of relatively mature, except still abnormal, white blood cells. Usually it takes months or years to progress the cells produce at a faster rate than normal cells, resulting in many abnormal white blood cells in the blood. Chronic leukemia mostly occurs in older people, but can also occur in any age group. There is Chronic Lymphocytic Leukemia that often occurs to adult older than the age of 55. There is also Chronic Myelogenous Leukemia that occurs mainly in adults and a very few amount of children develop the disease.Acute lymphocytic leukemia is the most common type of leukemia in young children. This disease also affects adults, especially at age 65 and older. This type of Leukemia is a cancer of the white blood cells, characterized by the overproduction and continuous multiplication of malignant and immature white blood in the bone marrow. It is a hematological malignancy. (Pakhare 2004)The Bone nub is a soft highly vascular modified connective tissue that occupies the cavities and cancellate part of most bones and occurs in two forms a a whitish or yellowish bone marrow consisting chiefly of fat cells and predominating in the cavities of the long bones-called also yellow marrow b a reddish bone marrow containing little fat, being the chief lieu of red blood cell and blood granulocyte format ion, and occurring in the normal adult further in cancellous tissue especially in real flat bones-called also red marrow (Merriam-Webster Dictionary.)When a Bone effect starts to produce abnormally white blood cells, it is called leukemia. When the white blood cells are being produced in a vast amount and at a fast rate, it starts to feast on the erythrocytes therefore leaving the body with out any blood. Blood is what keeps the human body alive. It carries the oxygen through our entirely body. There three ways to treat leukemia and that is Chemotherapy, Radiation Therapy, and Bone Marrow Transplants.Chemotherapy uses drugs to cut down the cancer cells. These drugs can be given intravenously, orally, subcutaneously, intramuscularly (injected into muscle), or intrathecally. But the chemotherapy treatment varies since there are different types of leukemia and not only does it kill the cancer cells but it also kills other cells.Radiation therapy plant life by damaging the genetic material (DNA) within cells, which prevents the cellsfrom growing and reproducing. Although the radiotherapy is directed at cancer cells, water-loving cells near the cancer cells may also be damaged. However, a goal of radiotherapy is to protect the healthy cells as much as possible, so that the benefit (destroying the cancer cells) outweighs the luck(harming healthy cells). (The Leukemia and Lymphoma Society 2009)Bone Marrow transplant replaces the diseased bone marrow with a healthier one. Bone marrow transplantation is carry out by the intravenous administration of bone marrow or cornerstone cells capable of reproducing themselves and repopulating an empty or defective bone marrow. Often, chemotherapy and/or irradiation therapy are required prior to the administration of the stem cells in society to eradicate the remaining defective bone marrow. For patients with cancer, the chemotherapy and radiation therapy also are effective at treating the cancer. (Cutler 2005)But what are the positive and negative outcomes of these treatments? Although Chemotherapy does manage to kill most cancerous cell it also comes with some side- effectuate. For interpreter nausea, vomiting, hair loss, fatigue, anemia, mouth sores, taste and smell changes, infection, diarrhea, menopause, and infertility. The side-effects of Radiation Therapy treatment are similar to the ones of Chemotherapy. A bone marrow may not be successful because of disease recurrence or regimen-related toxicity. Regimen-related toxicity refers to side effects that patients may experience during the course of transplantation. These side effects include graft-vs-host disease (GvHD), graft rejection, bacterial infections, fungal infections, viral infections, gastrointestinal and hepatic complications, neurologic complications, pulmonary complications, and late effects after stem cell transplant.Although these treatments can help people with leukemia it can also kill them. It might kill cancerous cells bu t it also kills other good cells.
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